Cadmium induces epithelial-mesenchymal transition and migration of renal cancer cells by increasing PGE2 through a cAMP/PKA-COX2 dependent mechanism.

This study might contribute to understanding of the mechanism of Cd-induce progression of renal cancer and future studies on the prevention and therapy of renal cell carcinomas.
PMID: 33254385 [PubMed - in process]

Source: Ecotoxicology and Environmental Safety - December 3, 2020 Category: Environmental Health Authors: Shi H, Sun X, Kong A, Ma H, Xie Y, Cheng D, Wong CKC, Zhou Y, Gu J Tags: Ecotoxicol Environ Saf Source Type: research