The association of dietary flavonoids, magnesium and their interaction effect with metabolic syndrome in Chinese adults: a prospective cohort study.

The association of dietary flavonoids, magnesium and their interaction effect with metabolic syndrome in Chinese adults: a prospective cohort study. Br J Nutr. 2020 Dec 01;:1-32 Authors: Jin S, Liu J, Jia Y, Han T, Zhao X, Sun C, Na L Abstract To systematically analyze the association of the specific flavonoids, magnesium and their interactions from different food sources with metabolic syndrome (MetS) and its components in cohort study. A total of 6417 participants aged from 20 to 74 years from the Harbin Cohort Study on Diet, Nutrition and Chronic Non-communicable Diseases (HDNNCDS) were included. Multivariate logistic regression analyses, forest plot and Cubic splines were performed in the study. After a 5.3-year follow-up, 1283 incident cases of MetS were reported. Those with a higher total flavonoids intake had a lower risk of MetS (fourth vs. first quartile, relative risk (RR): 0.58; 95% CI: 0.37, 0.93; P = 0.024) and central obesity (0.56; 0.33, 0.95; P = 0.032). Further analysis showed that the specific flavonoids quercetin, kaempferol, isorhamnetin, luteolin, and flavonoids from fruits, potatoes and legumes had the similar associations with the risk of MetS and central obesity (P < 0.05 for all). A higher intake of total flavonoids, quercetin and luteolin combined with high level of magnesium was more strongly associated with a lower risk of MetS (0.60; 0.45, 0.81 for total; 0.61; 0.45, 0.82 for quercetin; 0.52; 0.38, 0.7...
Source: The British Journal of Nutrition - Category: Nutrition Authors: Tags: Br J Nutr Source Type: research