Limited Specificity of Serologic Tests for SARS-CoV-2 Antibody Detection, Benin.

Limited Specificity of Serologic Tests for SARS-CoV-2 Antibody Detection, Benin. Emerg Infect Dis. 2020 Dec 01;27(1): Authors: Yadouleton A, Sander AL, Moreira-Soto A, Tchibozo C, Hounkanrin G, Badou Y, Fischer C, Krause N, Akogbeto P, de Oliveira Filho EF, Dossou A, Brünink S, Aïssi MAJ, Djingarey MH, Hounkpatin B, Nagel M, Drexler JF Abstract We used commercially available ELISAs to test 68 samples from coronavirus disease cases and prepandemic controls from Benin. We noted <25% false-positive results among controls, likely due to unspecific immune responses elicited by acute malaria. Serologic tests must be carefully evaluated to assess coronavirus disease spread and immunity in tropical regions. PMID: 33261717 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/33261717?dopt=Abstract

Source: Emerging Infectious Diseases - December 1, 2020 Category: Infectious Diseases Authors: Yadouleton A, Sander AL, Moreira-Soto A, Tchibozo C, Hounkanrin G, Badou Y, Fischer C, Krause N, Akogbeto P, de Oliveira Filho EF, Dossou A, Brünink S, Aïssi MAJ, Djingarey MH, Hounkpatin B, Nagel M, Drexler JF Tags: Emerg Infect Dis Source Type: research