Pathogenic effects of inhibition of mTORC1/STAT3 axis facilitates Staphylococcus aureus-induced pyroptosis in human macrophages

Pyroptosis is a recently identified pathway of caspase-mediated cell death in response to microbes, lipopolysaccharide, or chemotherapy in certain types of cells. However, the mechanism of how pyroptosis is re...

Source: Cell Communication and Signaling - November 30, 2020 Category: Molecular Biology Authors: Ruiyuan Yao, Yuhao Chen, Huifang Hao, Zhixin Guo, Xiaoou Cheng, Yuze Ma, Qiang Ji, Xiaoru Yang, Yanfeng Wang, Xihe Li and Zhigang Wang Tags: Research Source Type: research