Right ventricular area strain from 3-dimensional echocardiography: Mechanistic insight of right ventricular dysfunction in pediatric pulmonary hypertension

Right ventricular (RV) function is a major contributor to the outcome of pulmonary arterial hypertension (PAH). Adult studies demonstrated that regional and global changes in RV deformation are prognostic in PAH using 3-dimensional echocardiography (3DE). However, regional and global dynamic changes in RV mechanics have not been described in pediatric PAH. We compared 3DE RV regional and global deformation between pediatric patients who had associated PAH with congenital heart disease (APAH-CHD), pediatric patients who had idiopathic PAH (IPAH), and normal controls, and evaluated the clinical outcomes.

Source: The Journal of Heart and Lung Transplantation - November 14, 2020 Category: Transplant Surgery Authors: Pei-Ni Jone, Nicolas Duchateau, Zhaoxing Pan, D. Dunbar Ivy, Pamela Moceri Tags: ORIGINAL CLINICAL SCIENCE Source Type: research