An allosteric interleukin-1 receptor modulator mitigates inflammation and photoreceptor toxicity in a model of retinal degeneration

Inflammation and particularly interleukin-1 β (IL-1β), a pro-inflammatory cytokine highly secreted by activated immune cells during early AMD pathological events, contribute significantly to retinal neurodegene...

Source: Journal of Neuroinflammation - November 27, 2020 Category: Neurology Authors: Rabah Dabouz, Colin W. H. Cheng, P énélope Abram, Samy Omri, Gael Cagnone, Khushnouma Virah Sawmy, Jean-Sébastien Joyal, Michel Desjarlais, David Olson, Alexander G. Weil, William Lubell, José Carlos Rivera and Sylvain Chemtob Tags: Research Source Type: research