Suppression of Hippo Pathway by Food Allergen Exacerbates Intestinal Epithelia Instability and Facilitates Hypersensitivity

ConclusionsBoth in vivo and in vitro data demonstrated that the two food allergens suppressed Hippo pathway by downregulating TAZ expression, resulting in intestinal epithelia instability, and finally leading to hypersensitivity reactions. These findings provided potential therapeutic targets and molecular markers for food allergy, and provide dietary guidelines for allergenic individuals.This article is protected by copyright. All rights reserved

Source: Molecular Nutrition and Food Research - November 27, 2020 Category: Food Science Authors: Chong Wang, Wanglei lin, Yanbo Wang, Linglin Fu Tags: Research Article Source Type: research