HLA molecule expression on the surface of cells and microparticles in platelet concentrates.

CONCLUSION: Platelets or residual cells remaining after leukoreduction are not the only source of HLA Class I molecules in PCs, highlighting the contribution of MPs to alloimmunization mechanisms. These data may be relevant for the development of new transfusion guidelines.
PMID: 33241556 [PubMed - as supplied by publisher]

Source: Transfusion - November 25, 2020 Category: Hematology Authors: Pannetier L, Tamagne M, Bocquet T, Pirenne F, Ansart-Pirenne H, Vingert B Tags: Transfusion Source Type: research