Two new RHD alleles with deletions spanning multiple exons.

CONCLUSIONS: Resolution of unclear or inconclusive results from targeted genotyping arrays often leads to the discovery of new alleles. The 5' Rhesus box may be a hot spot for genetic recombination events, such as the large deletions described in this report.
PMID: 33241598 [PubMed - as supplied by publisher]

Source: Transfusion - November 25, 2020 Category: Hematology Authors: Matteocci A, Monge-Ruiz J, Stef M, Apraiz I, Herrera-Del-Val L, Mancuso T, Fennell K, Lopez M, Larizgoitia-Martin Y, Nespoli G, Rubia-Tejero M, Collaretti A, Pierelli L, Ochoa-Garay G Tags: Transfusion Source Type: research