Bioactive natural products from the genus Salinospora: a review.

Bioactive natural products from the genus Salinospora: a review.
Arch Pharm Res. 2020 Nov 25;:
Authors: Kim H, Kim S, Kim M, Lee C, Yang I, Nam SJ
Abstract
Actinomycetes are an important source for bioactive secondary metabolites. Among them, the genus Salinispora is one of the first salt obligatory marine species worldwide and is typically found in various types of substrates in tropical and subtropical marine environments including sediments and marine organisms. This genus produces a wide range of chemical scaffolds and bioactive compounds such as lomaiviticins, cyclomarins, rifamycins, salinaphthoquinones, and salinosporamides. This review arranged Salinispora derived secondary metabolites according to the three species that comprise the genus. Moreover, muta- and semi-synthesis analogs derived from salinosporamide were also described in this review.
PMID: 33237436 [PubMed - as supplied by publisher]

Source: Archives of Pharmacal Research - November 25, 2020 Category: Drugs & Pharmacology Authors: Kim H, Kim S, Kim M, Lee C, Yang I, Nam SJ Tags: Arch Pharm Res Source Type: research