Nebulization of High-Dose Poractant Alfa in Newborn Piglets on Nasal Continuous Positive Airway Pressure Yields Therapeutic Lung Doses of Phospholipids
Conclusion Nebulization was well tolerated, and the mean lung dose of phospholipids was above 100 mg/kg, that is, not different from the instillation group. These experimental findings suggest that it may be feasible to reach therapeutic lung doses of phospholipids by surfactant nebulization during nCPAP.
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Source: American Journal of Perinatology - Category: Perinatology & Neonatology Authors: Nord, Anders Bianco, Federico Salomone, Fabrizio Ricci, Francesca Schlun, Martin Linner, Rikard Cunha-Goncalves, Doris Tags: Original Article Source Type: research
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