Evaluating the efficacy and safety of the myrtle ( Myrtus communis ) in treatment and prognosis of patients suspected to novel coronavirus disease (COVID-19): study protocol for a randomized controlled trial

This study aims at investigating the effect ofM. communis fruit for treatment of COVID-19 disease.MethodsWe are performing an open-label randomized controlled trial on outpatients clinically suspected to COVID-19 disease in the age range of 18 –65 years old with mild to moderate symptoms and without respiratory distress. Patients in both groups (M. communis and control) receive conventional therapy, but those inM. communis group getM. communis preparation in addition to conventional therapy. Intervention will continue for 5  days and the study outcomes including clinical status as well as mortality rate and adverse effects will be measured up to 14 days.DiscussionThe protocol describes the design of an ongoing randomized controlled trial to establish the evidence for the usage of water extract ofM. communis fruit in clinically suspected COVID-19 disease and identify any safety concerns.Trial registrationThe trial has been registered at the Iranian Registry of Clinical Trials website under the code  IRCT20180923041093N3 on March 28th, 2020 (https://www.irct.ir/trial/46721). The results will be disseminated through manuscript publications and presentations to scientific meetings.
Source: Trials - Category: Research Source Type: clinical trials