Optimal use of intravenous tranexamic acid for hemorrhage prevention in pregnant women

Every 2 minutes there is a pregnancy related death worldwide, with one third due to severe postpartum hemorrhage (PPH). While international trials demonstrated efficacy of 1,000 mg TXA in treating PPH, to our knowledge there are no dose finding studies of TXA in pregnant women for PPH prevention.

Source: American Journal of Obstetrics and Gynecology - November 26, 2020 Category: OBGYN Authors: Homa K. AHMADZIA, Naomi L.C. LUBAN, Shuhui LI, Dong GUO, Adam MISZTA, Jogarao V.S. GOBBURU, Jeffrey S. BERGER, Andra H. JAMES, Alisa S. WOLBERG, John VAN DEN ANKER Tags: Original Research: Obstetrics Source Type: research