Hemodynamic study in 3D printed stenotic coronary artery models: experimental validation and transient simulation.

Hemodynamic study in 3D printed stenotic coronary artery models: experimental validation and transient simulation. Comput Methods Biomech Biomed Engin. 2020 Nov 23;:1-14 Authors: Carvalho V, Rodrigues N, Ribeiro R, Costa PF, Teixeira JCF, Lima RA, Teixeira SFCF Abstract Atherosclerosis is a progressive disease that can significantly reduce blood supply to vital organs, being one of the main causes of death worldwide. In this work, a numerical and experimental study in 3 D printed stenotic coronary arteries is presented, considering both steady and pulsatile blood flow conditions, is presented. The results revealed that a degree of stenosis superior to 50% creates disturbed flows downstream of the contraction, with an accented increase in the wall shear stress measurements at the stenosis throat. Finally, the multiphase mixture was investigated and compared with a single-phase modelling, and only slight differences were observed right after the stenosis throat. PMID: 33225743 [PubMed - as supplied by publisher]
Source: Computer Methods in Biomechanics and Biomedical Engineering - Category: Biomedical Engineering Authors: Tags: Comput Methods Biomech Biomed Engin Source Type: research