Population pharmacokinetics of micafungin over repeated doses in critically ill patients: a need for a loading dose?
ConclusionsA loading dose of up to 300 mg of micafungin is needed for the treatment of invasive candidiasis in ICU patients while a maintenance dose of up to 200 mg can be considered in empirical antifungal treatment.
Source: Journal of Pharmacy and Pharmacology - Category: Drugs & Pharmacology Authors: Iasonas Kapralos,
Efstratios Mainas,
Efthymios Neroutsos,
Stella Apostolidi,
Maria Siopi,
Olympia Apostolopoulou,
George Dimopoulos,
Helen Sambatakou,
Georgia Valsami,
Joseph Meletiadis,
Aristides Dokoumetzidis Tags: Research Paper Source Type: research