K284-6111 alleviates memory impairment and neuroinflammation in Tg2576 mice by inhibition of Chitinase-3-like 1 regulating ERK-dependent PTX3 pathway

Alzheimer ’s disease (AD) is one of the most prevalent neurodegenerative disorders characterized by gradual memory loss and neuropsychiatric symptoms. We have previously demonstrated that the 2-({3-[2-(1-cycloh...

Source: Journal of Neuroinflammation - November 22, 2020 Category: Neurology Authors: Hyeon Joo Ham, Yong Sun Lee, Jaesuk Yun, Dong Ju Son, Hee Pom Lee, Sang-Bae Han and Jin Tae Hong Tags: Research Source Type: research