Dose- and time-dependent effects of hyaluronidase on structural cells and the extracellular matrix of the skin

ConclusionHYAL is a bioactive enzyme that exerts multiple effects on the HA-metabolism as well as on the structural cells of the skin. Our results indicate that HYAL promotes wound healing and exerts a dose-dependent induction of HA-synthesis in structural cells of the skin. Herein, interestingly the most significant induction of HAS and HA were observed for the lowest concentration of HYAL.
Source: European Journal of Medical Research - Category: Research Source Type: research