Enhanced IgG1 ‐mediated antibody response towards thymus‐dependent immunization in CXCR1‐deficient mice

ConclusionOur data demonstrate a previously unknown relevance of CXCR1 for the production of specific IgG1 in response to vaccination. These findings identify CXCR1 as a promising candidate for future studies on the regulation of adaptive antibody responses.

Source: Immunity, Inflammation and Disease - November 23, 2020 Category: Allergy & Immunology Authors: Jennifer Jaufmann, Melanie Carevic, Leyla T ümen, Derya Eliacik, Fee Schmitt, Dominik Hartl, Sandra Beer‐Hammer Tags: ORIGINAL RESEARCH Source Type: research