The eIF4E homolog 4EHP (eIF4E2) regulates hippocampal long-term depression and impacts social behavior

ConclusionsTogether these results demonstrate an important role of 4EHP in regulating hippocampal plasticity and ASD-associated social behaviors, consistent with the link between mutations inGIGYF2 and ASD.

http://link.springer.com/10.1186/s13229-020-00394-7

Source: Molecular Autism - November 23, 2020 Category: Molecular Biology Source Type: research