Skeletal Muscle Extracellular Matrix Remodeling with Worsening Glycemic Control in Nonhuman Primates.

This report supports that rising blood glucose values incite ECM remodeling and reduce SkM capillarization, and that targeting ECM would be a rational approach to improve health with metabolic disease.
PMID: 33206559 [PubMed - as supplied by publisher]

Source: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology - November 18, 2020 Category: Physiology Authors: Ruggiero AD, Davis A, Sherrill C, Westwood B, Hawkins GA, Palmer ND, Chou JW, Reeves T, Cox LA, Kavanagh K Tags: Am J Physiol Regul Integr Comp Physiol Source Type: research