Closing in on PFAPA syndrome as “bad luck”

Periodic fever, aphthous stomatitis, pharyngitis, and adenitis (PFAPA) has been a fascinating condition since its description in 1987. Otherwise healthy young children have clockwork timing of episodes every 3-5 weeks in which sudden onset of high fever is followed by the other characteristic findings of the PFAPA name. After 3-4 days the episode ends just as abruptly and complete wellness ensues, until the next episode. After 4-6 years, intervals lengthen and in the majority of patients, episodes disappear.

Source: The Journal of Pediatrics - November 21, 2020 Category: Pediatrics Authors: Sarah S. Long Tags: The Editors' Perspectives Source Type: research