Pharmacokinetics and efficacy of atropine sulfate/obidoxime chloride Co-formulation against VX in a Guinea pig model.

In conclusion, ATR/OBI has been proven to be efficacious against exposure to VX and there were no PK interactions between ATR and OBI when administered as a co-formulation.
PMID: 33212192 [PubMed - as supplied by publisher]

Source: Regulatory Toxicology and Pharmacology : RTP - November 16, 2020 Category: Toxicology Authors: Kentrop J, Savransky V, Klaassen SD, van Groningen T, Bohnert S, Cornelissen AS, Cochrane L, Barry J, Joosen MJA Tags: Regul Toxicol Pharmacol Source Type: research