Famciclovir leads to failure of hematopoiesis, but may have the benefit of relieving myeloid expansion in MDS-like zebrafish.

This study reveals that FCV functions as a double-edged sword, with hematotoxicity at a high level, but that appropriate FCV treatment may be beneficial for the treatment of MDS.
PMID: 33207248 [PubMed - as supplied by publisher]

Source: Toxicology and Applied Pharmacology - November 15, 2020 Category: Toxicology Authors: Li J, Meng P, Zhou R, Zhang Y, Lin Q Tags: Toxicol Appl Pharmacol Source Type: research