Cognitive and behavioral risk factors for low quality of life in survivors of childhood acute lymphoblastic leukemia.

CONCLUSIONS: ALL survivors experience diffuse cognitive, behavioral, and motor impairments, which are associated with reduced quality of life. These findings underscore the need to address these challenges in ALL survivors.
IMPACT: Compared with cancer-free peers, parents of childhood acute lymphoblastic leukemia survivors treated with chemotherapy only reported reduced quality of life. Math difficulties and behavioral problems increased the risk for reduced quality of life. Reduced quality of life is associated with mild cognitive and behavioral difficulties, suggesting that even relatively mild impairments have broad implications for ALL survivors. Screening and early intervention targeting cognitive and behavioral function may enhance quality of life for ALL survivors.
PMID: 33203967 [PubMed - as supplied by publisher]

Source: Pediatric Research - November 17, 2020 Category: Pediatrics Authors: van der Plas E, Spencer Noakes TL, Butcher DT, Weksberg R, Galin-Corini L, Wanstall EA, Te P, Hopf L, Guger S, Hitzler J, Schachar RJ, Ito S, Nieman BJ Tags: Pediatr Res Source Type: research