Oral P. gingivalis impairs gut permeability and mediates immune responses associated with neurodegeneration in LRRK2 R1441G mice

The R1441G mutation in the leucine-rich repeat kinase 2 (LRRK2) gene results in late-onset Parkinson ’s disease (PD). Peripheral inflammation and gut microbiota are closely associated with the pathogenesis of P...

Source: Journal of Neuroinflammation - November 19, 2020 Category: Neurology Authors: Yu-Kun Feng, Qiong-Li Wu, Yan-Wen Peng, Feng-Yin Liang, Hua-Jing You, Yi-Wei Feng, Ge Li, Xue-Jiao Li, Shu-Hua Liu, Yong-Chao Li, Yu Zhang and Zhong Pei Tags: Research Source Type: research