Urea transporter proteins as targets for small-molecule diuretics
Nature Reviews Nephrology 11, 113 (2015).
doi:10.1038/nrneph.2014.219
Authors: Cristina Esteva-Font, Marc O. Anderson & Alan S. Verkman
Conventional diuretics such as furosemide and thiazides target salt transporters in kidney tubules, but urea transporters (UTs) have emerged as alternative targets. UTs are a family of transmembrane channels expressed in a variety of mammalian tissues, in particular the kidney. UT knockout mice and humans
Source: Nature Reviews Nephrology - Category: Urology & Nephrology Authors: Cristina Esteva-FontMarc O. AndersonAlan S. Verkman Tags: Review Source Type: research
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