Causes and pathogenesis of focal segmental glomerulosclerosis

Nature Reviews Nephrology 11, 76 (2015). doi:10.1038/nrneph.2014.216 Author: Agnes B. Fogo Focal segmental glomerulosclerosis (FSGS) describes both a common lesion in progressive kidney disease, and a disease characterized by marked proteinuria and podocyte injury. The initial injuries vary widely. Monogenetic forms of FSGS are largely due to alterations in structural genes of the podocyte, many of
Source: Nature Reviews Nephrology - Category: Urology & Nephrology Authors: Tags: Review Source Type: research