Fibrosis: Dysfunctional fatty acid oxidation in renal fibrosis

Nature Reviews Nephrology 11, 64 (2015). doi:10.1038/nrneph.2014.244 Author: Susan J. Allison Accumulation of lipid in tubular epithelial cells has been proposed to have a pathogenic role in the development of renal fibrosis. New findings, however, indicate that dysfunctional fatty acid oxidation rather than intracellular lipid accumulation per se induces the development of renal fibrosis.Fibrosis
Source: Nature Reviews Nephrology - Category: Urology & Nephrology Authors: Tags: Research Highlight Source Type: research