Basic research: Role of mTOR in regulation of ENaC activity

Nature Reviews Nephrology 11, 64 (2015). doi:10.1038/nrneph.2014.236 The epithelial Na+ channel (ENaC) is a key regulator of Na+ homeostasis and new findings show that mammalian target of rapamycin (mTOR) can modulate ENaC function. Gleason et al. found that administration of mTOR inhibitors to mice prevented mTOR-dependent
Source: Nature Reviews Nephrology - Category: Urology & Nephrology Tags: Research Highlight Source Type: research