Glomerular disease: Thrombospondin type-1 domain-containing 7A—a new player in membranous nephropathy

Nature Reviews Nephrology 11, 63 (2015). doi:10.1038/nrneph.2014.227 Author: Susan J. Allison In 2009, the podocyte receptor phospholipase A2 receptor 1 (PLA2R1) was identified as the first major autoantigen involved in the pathogenesis of adult idiopathic membranous nephropathy (iMN). Subsequent studies confirmed circulating autoantibodies to PLA2R1 in approximately 70% of affected patients; however, the cause of disease
Source: Nature Reviews Nephrology - Category: Urology & Nephrology Authors: Tags: Research Highlight Source Type: research