Differences in predicted warfarin dosing requirements between Hmong and East Asians using genotype ‐based dosing algorithms

ConclusionThe unique allele frequencies related to warfarin when combined with non ‐genetic factors observed in the Hmong translate into clinically relevant differences in predicted maintenance dose requirements for Hmong versus East Asians.

Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - November 17, 2020 Category: Drugs & Pharmacology Authors: Boguang Sun, Ya ‐Feng Wen, Kathleen A. Culhane‐Pera, Muaj Lo, Txia Xiong, Koobmeej Lee, Kerui Peng, Bharat Thyagarajan, Jeffrey R. Bishop, Heather Zierhut, Robert J. Straka Tags: ORIGINAL RESEARCH ARTICLE Source Type: research