Prognosis after surgery for multiple endocrine neoplasia type 1-related pancreatic neuroendocrine tumors: Functionality matters

Metastasized pancreatic neuroendocrine tumors are the leading cause of death in patients with multiple endocrine neoplasia type 1. Aside from tumor size, prognostic factors of pancreatic neuroendocrine tumors are largely unknown. The present study aimed to assess whether the prognosis of patients with resected multiple endocrine neoplasia type 1-related nonfunctioning pancreatic neuroendocrine tumors differs from those with resected multiple endocrine neoplasia type 1-related insulinomas and assessed factors associated with prognosis.

Source: Surgery - November 18, 2020 Category: Surgery Authors: Dirk-Jan van Beek, Sjoerd Nell, Helena M. Verkooijen, Inne H.M. Borel Rinkes, Gerlof D. Valk, DutchMEN Study Group (DMSG), Menno R. Vriens, International MEN1 Insulinoma Study Group, Pierre Goudet, French Endocrine Tumor Study Group (GTE), Nicolas Santucc Source Type: research