Whole genome analysis of extensively drug-resistant Acinetobacter bau-mannii clinical isolates in Thailand.

CONCLUSIONS: Whole-genome sequencing revealed both blaOXA-23 harboring XDRAB isolates were clustered under interna-tional clone II with difference STs and carrying multiple antimicrobial-resistant genes conferred their resistance to antimi-crobial agents. Inactivation of antimicrobials and target modification by enzymes, and pumping antibiotics by efflux pump are mainly resistance mechanism of the XDRAB in this study. PMID: 33200701 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/33200701?dopt=Abstract

Source: Infectious Disorders Drug Targets - November 16, 2020 Category: Infectious Diseases Authors: Chopjitt P, Kerdsin A, Takeuchi D, Hatrongjit R, Boueroy P, Akeda Y, Tomono K, Hamada S Tags: Infect Disord Drug Targets Source Type: research