Whole genome analysis of extensively drug-resistant Acinetobacter bau-mannii clinical isolates in Thailand.
CONCLUSIONS: Whole-genome sequencing revealed both blaOXA-23 harboring XDRAB isolates were clustered under interna-tional clone II with difference STs and carrying multiple antimicrobial-resistant genes conferred their resistance to antimi-crobial agents. Inactivation of antimicrobials and target modification by enzymes, and pumping antibiotics by efflux pump are mainly resistance mechanism of the XDRAB in this study.
PMID: 33200701 [PubMed - as supplied by publisher]
Source: Infectious Disorders Drug Targets - Category: Infectious Diseases Authors: Chopjitt P, Kerdsin A, Takeuchi D, Hatrongjit R, Boueroy P, Akeda Y, Tomono K, Hamada S Tags: Infect Disord Drug Targets Source Type: research