Moving from innovation to validation with independent sample testing Editorial on Neural correlates of positive emotion processing that distinguish healthy youth at familial risk for bipolar versus major depressive disorder

It is well established that family history is the most important known risk factor for the development of a mood disorder. 1 Approximately 25% of at-risk offspring will develop a mood disorder; 1,2 yet this is only slightly higher than the lifetime rate of a mood disorder overall of 21.4%.3 These statistics suggest heterogeneity within mood disorders generally and within those at familial risk. More information, particularly in the form of trait level biomarkers, is sorely needed to accurately predict mood disorder risk and development.
Source: Journal of the American Academy of Child and Adolescent Psychiatry - Category: Psychiatry Authors: Tags: Editorial Source Type: research