The efficacy of in vivo administration of Apremilast on mesenchymal stem cells derived from psoriatic patients

ConclusionApremilast treatment influences the expression of VEGF, iNOS and IDO not only by keratinocytes but also by MSCs, restoring their intrinsic profile and their natural anti-inflammatory action, and decreasing the auto-inflammatory process that underpins the development of psoriasis.
Source: Inflammation Research - Category: Research Source Type: research