Normal fat mass cannot be reliably estimated in typical pharmacokinetic studies
ConclusionIn typical pharmacokinetic studies, NFM should be used with caution because theFfat estimates have low precision. The estimation of Ffat should always be preceded by careful study design evaluation before planning a study, to ensure that the design and sample size is sufficient to apply this potentially useful methodology.
Source: European Journal of Clinical Pharmacology - Category: Drugs & Pharmacology Source Type: research
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