p75NTR Promotes Astrocyte Proliferation in Response to Cortical Stab Wound.

In conclusion, our results suggested that p75NTR upregulation in astrocytes after brain injury induces cell cycle entry by promoting CDK2 expression and promoting astrocyte proliferation. Our findings provided a better understanding of astrocytic responses after cortical stab wound injury in mice.
PMID: 33201418 [PubMed - as supplied by publisher]

Source: Cellular and Molecular Neurobiology - November 17, 2020 Category: Cytology Authors: Chen M, Guo L, Hao J, Ni J, Lv Q, Xin X, Liao H Tags: Cell Mol Neurobiol Source Type: research