Bile formation in long-term (1 week), ex situ perfused livers: Analysis and commentary

In the article by Eshmuminov et  al1 entitled “Bile formation in long term (1 week) ex situ perfused livers,” the authors explore a novel protocol for stimulation of bile flow during prolonged liver allograft machine perfusion. Using their previously developed machine perfusion system, which mimics physiological conditions th rough the inclusion of continuous artificial pancreatic monitoring and hormonal supplementation, dialysate-based blood filtration, and oxygenation,2 the authors show feasibility in a porcine transplantation model, followed with application of long-term monitoring to discarded human liver grafts.
Source: Surgery - Category: Surgery Authors: Source Type: research