Novel Dopamine D3 Receptor Antagonist Reduces Opioid Addiction-Like Behaviors in Rats

The dopamine D3 receptor antagonist VK4-116 reduced oxycodone self-administration in rats, as well as drug-seeking behaviors after oxycodone reinstatement following withdrawal. VK4-116 did not interfere with oxycodone ’s pain-relieving effects
Source: NIDA News - Category: Addiction Tags: NIDA Notes, Opioids, Basic Science, Treatment Research, Pain, Addiction Science Source Type: news