Flow Cytometric Assessment of AKT Signaling in Platelet Activation: An Alternative Diagnostic Tool for Small Volumes of Blood.

CONCLUSION:  An activation of the AKT-signal pathway by different agonists can clearly be detected on the flow cytometer, indicating that the visualization of signaling in platelets by flow cytometry might be an efficient alternative for light transmission aggregometry to test platelet function in children.
PMID: 33187007 [PubMed - in process]

Source: Hamostaseologie - November 1, 2020 Category: Hematology Authors: Althaus K, Wagner M, Marini I, Bakchoul T, Pelzl L Tags: Hamostaseologie Source Type: research