Application of 3D Printing Technology in Bone Tissue Engineering: A Review.

Application of 3D Printing Technology in Bone Tissue Engineering: A Review. Curr Drug Deliv. 2020 Nov 12;: Authors: Feng Y, Zhu S, Mei D, Li J, Zhang J, Yang S, Guan S Abstract Clinically, the treatment of bone defects remains a significant challenge, as it requires autogenous bone grafts or bone graft substitutes. However, the existing biomaterials often fail to meet the clinical requirements in terms of structural support, bone induction and controllable biodegradability. In the treatment of bone defects, 3D porous scaffolds have at-tracted much attention in the orthopedic field. In terms of appearance and microstructure, complex bone scaffolds created by 3D printing technology are similar to human bone. On this basis, the combination of active substances including cells and growth factors is more conducive to bone tissue reconstruction, which is of great significance for the personalized treatment of bone defects. With the continuous development of 3D printing technology, it has been widely used in bone defect repair as well as diagnosis and rehabilitation, creating an emerging industry with excellent market potential. Meanwhile, the di-verse combination of 3D printing technology with multi-disciplinary fields such as tissue engineering, digital medicine, and materials science has made 3D printing products with good biocompatibility, excellent osteo-inductive capacity and stable mechanical properties. In the clinical application o...
Source: Current Drug Delivery - Category: Drugs & Pharmacology Authors: Tags: Curr Drug Deliv Source Type: research