The diverse roles of T cell subsets in asthma.

The diverse roles of T cell subsets in asthma. Eur Ann Allergy Clin Immunol. 2020 Nov 12;: Authors: Regateiro FS, Botelho Alves P, Moura AL, Azevedo JP, Regateiro DT Abstract Summary: T cells are coordinators of the immune response and have been shown to play a central role in the pathophysiology of asthma. A good understanding of the T cells functions in asthma is important for therapeutic reasons, in particular for the choice of biological treatments in severe asthma. Although classically considered a Th2 disease, it is now clear that other types of T cells contribute for the pathophysiology and the heterogeneity of asthma. We here review how the different subsets of T cells are involved in the different phenotypes-endotypes of asthma and how this may influence the treatment of the disease. PMID: 33182992 [PubMed - as supplied by publisher]
Source: European Annals of Allergy and Clinical Immunology - Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research