A qualitative awake EEG score for the diagnosis of continuous spike and waves during sleep (CSWS) syndrome in self-limited focal epilepsy (SFE): a case-control study

Epileptic encephalopathy (EE) with continuous spike and waves during sleep (CSWS) including Landau-Kleffner syndrome (LKS) is a focal epilepsy syndrome of childhood characterised by the combination of regression in cognitive, behavioural and psychiatric functioning and a characteristic electroencephalographic (EEG) pattern, i.e. focal interictal epileptiform discharges (IED) that are activated in NREM sleep stages and tend to spread over the whole scalp [1]. Some cases are related to a specific aetiology (structural cerebral lesion or genetic mutation), but in most cases the aetiology is unknown.

Source: Seizure: European Journal of Epilepsy - November 17, 2020 Category: Neurology Authors: Alec Aeby, Roberto Santalucia, Audrey Van Hecke, Andrea Nebbioso, Justine Vermeiren, Nicolas Deconinck, Xavier De Ti ège, Patrick Van Bogaert Source Type: research