Soluble epoxide hydrolase inhibitors improve angiogenic function of endothelial progenitor cells via ERK/p38-mediated miR-126 upregulation in myocardial infarction mice after exercise.

This study showed that sEHi promoted miR-126 expression, which might be related to the beneficial effect of sEHi on EPC functions in MI mice under exercise conditions, by increasing ERK and p38 MAPK phosphorylation and inhibiting Spred1. PMID: 33188851 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/33188851?dopt=Abstract

Source: Experimental Cell Research - November 11, 2020 Category: Cytology Authors: Gui Y, Chen J, Hu J, Liao C, Ouyang M, Deng L, Yang J, Xu D Tags: Exp Cell Res Source Type: research