Multicenter Evaluation of Xpert Carba-R Assay for detection and identification of the carbapenemase genes in rectal swabs and clinical isolates

Quick detection of carbapenemase-producing organisms is clinically desirable for hospital infection control and antibiotic stewardship. In this multicenter study, Xpert Carba-R assay was evaluated for detection the five carbapenemase genes (blaKPC, blaNDM, blaIMP, blaOXA-48 and blaVIM) in 2,404 non-duplicate rectal swabs of admitted inpatients and 521 Gram-negative isolates from four tertiary hospitals in China, compared to the reference growth-based method with DNA sequence analysis of colonies.
Source: Journal of Molecular Diagnostics - Category: Pathology Authors: Tags: Regular Article Source Type: research