Letter in response to Badagliacca et al., Multi-dimensional assessment and cluster analysis for idiopathic pulmonary arterial hypertension phenotyping (JHLT-D-20-00956)

We thank our colleagues for their thoughtful comments. As the field is moving forward, it becomes increasingly clear that the term idiopathic pulmonary arterial hypertension (IPAH) does not describe a homogenous and well-defined disease but a basket full of pulmonary vascular disorders that have not much more in common than the presence of pre-capillary pulmonary hypertension and the absence of causative factors. Our cluster analysis focused on demographics and clinical presentation but has implications for disease mechanisms, treatment and outcome.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: Case Anecdotes, Comments and Opinions Source Type: research