Direct postoperative protein S100B and NIRS monitoring in infants after pediatric cardiac surgery enrich early mortality assessment at the PICU

Cerebral injury resulting from cardiac surgery depicts a devastating complication that can have severe effects on the neurological outcome.1 While this can be attributed to the inherent nature of cardiac disease, with possible hypoxemia and cyanosis, the surgical procedure itself poses its own risk, owing in particular to the use of cardiopulmonary bypass (CPB); potentially leading to compromised circulation, hypoxia and systemic inflammation, as reported after adult cardiac surgery.2,3 The use of plasmatic cerebral biomarkers for detecting cerebral damage, such as neuromonitoring, has been well-established since the 1990s.

Source: Heart and Lung - November 1, 2020 Category: Intensive Care Authors: Stefan Irschik, Sabrina Stelzl, Johann Golej, Gerald Schlager, Daniel Zimpfer, Claudia Herbst, Ina Michel-Behnke, Erwin Kitzm üller, Eva Base, Michael Hermon Source Type: research