CircFAT1 promotes hepatocellular carcinoma progression via miR-30a-5p/REEP3 pathway.

In conclusion, circFAT1 sponges miR-30a-5p to regulate the expression of REEP3, thus promoting hepatocarcinogenesis. New HCC diagnosis or treatment strategies may be developed from circFAT1 as a target.
PMID: 33179443 [PubMed - as supplied by publisher]

Source: J Cell Mol Med - November 11, 2020 Category: Molecular Biology Authors: Wei H, Yan S, Hui Y, Liu Y, Guo H, Li Q, Li J, Chang Z Tags: J Cell Mol Med Source Type: research