Response Surface Methodology to Optimize the Combination Treatment of Paclitaxel, Bufalin and Cinobufagin for Hepatoma Therapy.

CONCLUSION: The combination of BFL and CBF synergistically enhanced the potency of PTX against HepG2 cells. RSM could give an accurate evaluation for drug interactions and efficient prediction of optimum combination.
PMID: 33172373 [PubMed - as supplied by publisher]

Source: Combinatorial Chemistry and High Throughput Screening - November 10, 2020 Category: Chemistry Authors: Zhang J, Shu C, Yi X, Zhu J, Lian X, Wu Y Tags: Comb Chem High Throughput Screen Source Type: research