M030 rituximab-induced serum sickness in a pediatric patient with multiple autoimmune diseases and history of covid-19

Serum sickness, an immune-complex-mediated hypersensitivity reaction, is more common in adults than children. Rituximab has been reported as an agent that can cause serum sickness. This case discusses a pediatric patient who developed rituximab-induced serum sickness in the setting of a positive history of COVID-19 and recently diagnosed neuromyelitis optica, celiac disease, immune thrombocytopenia, and Sjogren ’s syndrome.

Source: Annals of Allergy, Asthma and Immunology - November 1, 2020 Category: Allergy & Immunology Authors: K. Nguyen, A. Kazatsky Source Type: research